Sophia College DCA is a post-graduate autonomous programme in Medical Technology. It was inaugurated in 1978 and is open to B.Sc. and M.Sc. students (both men and women) majoring in Microbiology, Biochemistry, Life Sciences, Zoology and Chemistry. It is a one-year programme with clinical rotations and internships in Mumbai's major hospitals. Besides eleven subjects related to Medical Technology, the course offers extra credit courses in English, Mathematics, Computers, Sales Management and Laboratory Management.

Sophia DCA is also recognized as the 16th year of education in most universities abroad. The job opportunities of such a programme range from employment as a bench technologist or a career in sales and management, to a career in research and development in India and abroad